Everything You Need to Know About Ozempic: The Miracle Medicine!

Shayma Abdulmanaf Shakir

Shayma Abdulmanaf Shakir

5th grade
Department of Pharmacy
TIU - Erbil

Anana Shamoon Shlaymoon

Anana Shamoon Shlaymoon

5th grade
Department of Pharmacy
TIU - Erbil

Diabetes is a chronic metabolic disorder that poses a severe threat to the health of individuals. It causes elevated levels of glucose (sugar) in the blood, which can lead to severe damage to the heart, blood vessels, eyes, kidneys, and nerves over time.

Diabetes affects approximately 422 million people worldwide, with the majority of cases reported in low- and middle-income countries. Shockingly, each year, 1.5 million deaths are directly attributed to diabetes. The incidence and prevalence of diabetes have been rapidly increasing over the past few decades, highlighting the urgent need for prevention and treatment measures.

 

A combination of genetic and lifestyle factors primarily causes diabetes. Factors such as family history, genetics, obesity, sedentary lifestyle, and poor diet can contribute to the development of diabetes.

Type 1 diabetes is an autoimmune condition, while Type 2 diabetes is often linked to lifestyle choices and genetics. Regular exercise and a healthy diet can help reduce the risk of developing Type 2 diabetes.

 

Anti-diabetic drugs aim to manage blood sugar levels in individuals with diabetes. They include:

  1. Insulin: Essential for Type 1 diabetes and sometimes used in Type 2.
  2. Metformin: Improves insulin sensitivity, commonly prescribed for Type 2 diabetes.
  3. Sulfonylureas: Stimulate insulin release from the pancreas.
  4. DPP-4 Inhibitors: Enhance insulin secretion and reduce glucose production.
  5. GLP-1 Receptor Agonists: Increase insulin release and slow digestion.
  6. SGLT2 Inhibitors: Reduce glucose reabsorption by the kidneys.
  7. Thiazolidinediones (TZDs): Improve insulin sensitivity.
  8. Meglitinides: Stimulate rapid insulin release.

Treatment plans vary, and drugs may be used alone or in combination depending on the type and severity of diabetes. Always consult a healthcare professional for personalized advice.

 

Semaglutide is a medication belonging to the class of GLP-1 receptor agonists. It is used in the treatment of Type 2 diabetes to help lower blood sugar levels. GLP-1 receptor agonists mimic the action of a naturally occurring hormone, glucagon-like peptide-1 (GLP-1), which stimulates insulin release and reduces glucose production by the liver. Semaglutide is typically administered as a subcutaneous injection once a week. It has shown efficacy in improving blood sugar control, and reducing body weight, and may have cardiovascular benefits. As with any medication, it should be prescribed and monitored by a healthcare professional.

While Ozempic, a GLP-1 receptor agonist, is primarily prescribed for managing Type 2 diabetes, it has been associated with weight loss as a secondary effect. Some individuals using Ozempic have experienced weight reduction as a part of their diabetes management. However, it’s crucial to note that the primary purpose of Ozempic is to control blood sugar levels.

 

While Ozempic (semaglutide) has shown efficacy in promoting weight loss, it’s essential to be aware of potential side effects. Common side effects may include nausea, vomiting, diarrhea, and abdominal pain. These side effects are often mild and tend to improve over time. If someone is considering Ozempic specifically for weight loss and does not have diabetes, they should consult with a healthcare professional. Weight loss medications, including GLP-1 receptor agonists, should be used under medical supervision, and the appropriateness of such medications depends on individual health conditions and needs. Always follow your healthcare provider’s recommendations for safe and effective use.

 

However, as with any medication, there can be more severe side effects. For Ozempic, these might include pancreatitis, kidney problems, or allergic reactions. It’s crucial to report any unusual or severe symptoms to a healthcare professional promptly.

 

Novo Nordisk, the Danish drugmaker, has carved out a new era in its 100-year history with the unparalleled success of its two products – Ozempic and Wegovy. This success has propelled the company to new heights, with a market value of $400 billion, making it the most valuable company in Europe by market cap.

The media hype surrounding the weight loss benefits of Ozempic has led to a massive surge in demand for the medication. However, it resulted in a shortage of the drug, leaving diabetic patients in a precarious situation and searching from one pharmacy to another, seeking alternative options to remain healthy and alive.

Intermittent Ozempic shortages are expected throughout 2024, according to the statement on the EMA’s website.